Why Your DNA Isn't Your Destiny

You have had a long-standing deal with biology: whatever choices you make during your life might ruin your short-term memory or make you gain weight t or could hasten death, but they won't change your genes — your actual DNA.

The answer lies beyond both nature and nurture. Bygren's data — along with those of many other scientists working separately over the past 20 years — have given birth to a new science called epigenetics.
At its most basic, epigenetics is the study of changes in gene activity that do not involve alterations to the genetic code but still get passed down to at least one successive generation.
These patterns of gene expression are governed by the cellular material — the epigenome — that sits on top of the genome, just outside it (hence the prefix epi-, which means above). It is these epigenetic "marks" that tell your genes to switch on or off, to speak loudly or whisper. It is through epigenetic marks that environmental factors like diet, stress and prenatal nutrition can make an imprint on genes that is passed from one generation to the next.
But the potential is staggering. For decades, we have stumbled around massive Darwinian roadblocks. DNA, we thought, was an ironclad code that we and our children and their children had to live by. Now we can imagine a world in which we can tinker with DNA, bend it to our will.

It will take geneticists and ethicists many years to work out all the implications, but be assured: the age of epigenetics has arrived.

(Time Magazine, Jan  2010)

Yours in health,
Rhonda

Turn on Your Genes!

The widely accepted dogma that your genes control your health destiny is quickly being uprooted by the emerging field of epigenetics. Epigenetics is probably the most important biological discovery since DNA!

How does it work? 

You’ve probably heard the debate of “nature vs. nurture” … meaning, is it the genetic code you received at conception or the environment in which you were raised that most influences your future health? The answer is both … but your actions, lifestyle and even your thoughts may have the most sway … and nothing is set in stone. Allow me to explain …
You’re in Control of Your Health Destiny

In his book, The Biology of Belief, Dr. Lipton explains the foundation of epigenetics, and how the true secret to life does not lie within your DNA, but rather within the mechanisms of the cell membrane. In this way -- which is contrary to conventional medical science -- it is actually the cell’s membrane -- operating in response to environmental signals picked up by the membrane’s receptors -- that control the “reading” of the genes inside.
For instance, researchers from the Linus Pauling Institute at Oregon State University recently explained at Experimental Biology 2010 how altered "histone modifications” can impact the expression of many degenerative diseases, ranging from cancer and heart disease to biopolar disorder and even aging itself.
Rod Dashwood, a professor of environmental and molecular toxicology and head of LPI's Cancer Chemoprotection Program, told EurekAlert:

"We believe that many diseases that have aberrant gene expression at their root can be linked to how DNA is packaged, and the actions of enzymes such as histone deacetylases, or HDACs.
As recently as 10 years ago we knew almost nothing about HDAC dysregulation in cancer or other diseases, but it's now one of the most promising areas of health-related research."
You have tumor suppressor genes in your body right now, and these genes are capable of stopping cancer cells in their tracks. These genes are present in ALL of your cells, but so are proteins called histones.
As Dr. Jean-Pierre Issa at the M.D. Anderson Cancer Center explains, histones can essentially “hug” DNA so tightly that it becomes “hidden from view for the cell.” If a tumor suppressor gene is hidden, it cannot be utilized, and in this way too much HDAC will “turn off” these cancer suppressors.
Now here’s where epigenetics comes in … there are many HDAC inhibitors out there that will essentially block the HDAC, allowing your tumor suppressor genes to activate and fight cancer. These HDAC inhibitors exist, at least in part, in common foods like broccoli and other cruciferous vegetables, garlic and onions.
By adding these foods to your diet, you are supporting your body’s ability to fight tumors.
And this is only one example of many.
You are in control of your genes … and are changing them often -- daily and perhaps even hourly -- based on the foods you eat, the air you breathe, and the thoughts you think. It’s your environment and lifestyle that dictates your tendency to express disease, and this new realization is set to make major waves in the future of disease prevention -- including one day educating people on how to fight disease at the epigenetic level.

(Dr. Mancola, 2010)
 
Yours in health,
Rhonda

Preventions to Allergic Reactions

Allergic Reaction


There are as many as 1,200 different types of grasses that can be found in the United States and surrounding areas. Yet despite the widespread nature of this species, the experts explain that only a handful of them actually trigger allergies. It is not the grass itself but the pollen it contains that causes the reaction to happen. In someone with allergies, when the pollen is breathed in, the immune system responds by releasing histamine and other chemicals that can spark a variety of allergy symptoms.
Some of the biggest grass pollen culprits include: Bermuda, Johnson, Timothy, Orchard and Sweet Vernal grass, and Kentucky bluegrass.

Other Factors

In addition to certain types of grasses sparking allergies, certain weather conditions also promote higher, or lower, grass pollen levels. These variables can include the temperature, time of day and rain.
Further, how the grass is maintained can also make a big difference, according to some landscapers. Lawns that are mowed frequently are usually less of a trigger than overgrown yards and can even trap pollen from nearby bushes, plants and trees. So if you are putting off taking care of your yard, this fact may inspire you to water, mow and fertilize your lawn, since all of these factors may just make a difference in minimizing your symptoms.
With so many different grasses to choose from, landscapers suggest planting a lawn that either won't bloom and produce pollen at all, or that will at least remain pollen free if you mow it regularly.

Other Prevention Tips

Other things you can do to minimize your reaction to grass pollen includes:

Wear a mask when you mow your lawn or better yet, have someone else do it.

Keep your grass well-maintained on a regular basis.

Minimize your actual lawn space and fill in some of the area with a rock garden and other allergy-free decorations.

Check pollen levels (you can find this information online or on the radio, television or newspaper) and stay indoors when counts are high.

Plan outdoor activities for late afternoon, when pollen is often lower.

Keep your home and car windows closed and run the air conditioning.

Always shower with very hot water after being outdoors. Also wash your clothes and bathe your pets often, too, since pollen can get trapped and brought inside otherwise.

Beat Grass Pollen

Grass pollen is a common allergy in the spring and summertime that can cause you to sneeze and cough, your nose and throat to itch and your eyes to water.

Allergic Reaction

There are as many as 1,200 different types of grasses that can be found in the United States and surrounding areas. Yet despite the widespread nature of this species, the experts explain that only a handful of them actually trigger allergies. It is not the grass itself but the pollen it contains that causes the reaction to happen. In someone with allergies, when the pollen is breathed in, the immune system responds by releasing histamine and other chemicals that can spark a variety of allergy symptoms.

Some of the biggest grass pollen culprits include: Bermuda, Johnson, Timothy, Orchard and Sweet Vernal grass, and Kentucky bluegrass.

Other Factors

In addition to certain types of grasses sparking allergies, certain weather conditions also promote higher, or lower, grass pollen levels. These variables can include the temperature, time of day and rain.

Further, how the grass is maintained can also make a big difference, according to some landscapers. Lawns that are mowed frequently are usually less of a trigger than overgrown yards and can even trap pollen from nearby bushes, plants and trees. So if you are putting off taking care of your yard, this fact may inspire you to water, mow and fertilize your lawn, since all of these factors may just make a difference in minimizing your symptoms.

With so many different grasses to choose from, landscapers suggest planting a lawn that either won't bloom and produce pollen at all, or that will at least remain pollen free if you mow it regularly.

Other Prevention Tips

Other things you can do to minimize your reaction to grass pollen includes:

• Wear a mask when you mow your lawn or better yet, have someone else do i
• Keep your grass well-maintained on a regular basis
• Minimize your actual lawn space and fill in some of the area with a rock garden and other allergy-free decorations.
• Check pollen levels (you can find this information online or on the radio, television or newspaper) and stay indoors when counts are high.
• Plan outdoor activities for late afternoon, when pollen is often lower. 
• Keep your home and car windows closed and run the air conditioning.
• Always shower with very hot water after being outdoors. Also wash your clothes and bathe your pets often, too, since pollen can get trapped and brought inside otherwise.

Yours in health,
Rhonda

What Triggers your Allergies?

If you suffer from allergies, you probably also have a pretty good idea of the things that make you sneeze. But have you ever wondered if your allergy triggers are the same as everyone else's? And do you think there could be other things that could be causing a reaction that you haven't yet identified?
Check out our list of the most common allergy triggers-and get some tips on how best to keep them from making you sick.
Trigger #1: Pollen

Whether it's pollen from grass, trees or flowering plants, this allergen is carried in the air and, as a result, is very easily spread. It also catches on your clothes, skin and hair, so it can be difficult to escape its effects anywhere. The worst time of year for pollen sufferers is usually spring and summer, but there are some pollens that do spread in winter, so beware.



Tip: Always take a hot shower and wash your hair and clothes right away after spending time outdoors to remove any pollen remnants that are trapped there.

Trigger #2: Mold

If you have a mold allergy, you know how pervasive this trigger can be. Mold spores can grow in moist and damp areas, such as kitchens, bathrooms and basements, too.
Tip: Avoid the risks of mold by keeping your home clean and dry and repairing leaks promptly.
Trigger #3: Dust Mites

Dust mites are tiny bugs that live in bedding, pillows, rugs, curtains and stuffed animals. Their waste can cause allergies so it's important to try to keep them away from you, and away from the areas where you sleep.
Tip: Remove curtains, carpeting and stuffed animals from your bedroom, keep your mattress and pillows encased in hypoallergenic covers and wash your bedding frequently in very hot water to minimize your exposure.

Trigger #4: Cockroaches

You may not know it but cockroaches can trigger your allergies. As gross as it sounds, their waste is actually what causes the reaction.

Tip: Keep your house very clean, avoid leaving out food and promptly remove crumbs to discourage the presence of cockroaches and other bugs.
Trigger #5: Bee Stings

No one likes to be stung by a bee, but for people with severe allergies, a bee sting can be life threatening. Therefore, it's important to carry an Epi-Pen in case you get bitten or stung in order to head off a serious reaction.

Tip: Avoid eating outdoors, using perfume or wearing brightly colored clothes outdoors, since all of these things can attract bugs your way. If you do find a bee, wasp or hornet's nest on your property, make sure to have it professionally removed.
Trigger #6: Peanuts and Tree Nuts

You're probably aware of the danger of peanut allergies, since this has been featured in the news a lot lately. For people with a severe reaction to any type of nuts, even coming in contact with someone else who recently had a nut product can be enough to trigger a reaction. Therefore, always carry an Epi-Pen just in case of an emergency.

Tip: Read labels to make sure there is no cross-contamination with nuts in any of the things you eat. You should also make your nut allergy known so people around you will go to great lengths to avoid eating peanut items in your presence. This is essential to helping you stay safe.

Trigger #7: Shellfish

If you've ever had a reaction to shellfish, you'll probably want to avoid all types, since an allergy to shellfish and other types of seafood can be very severe. If you're highly sensitive, even the steam from this item cooking can be enough to set a reaction in motion. Again, in an emergency, having an Epi-Pen can be a life saving step.
Tip: Always ask about ingredients when ordering a restaurant meal and make sure there's no danger of cross contamination if your allergy could be severe.
Trigger #8: Latex

Latex allergies have become more common in recent years. If you work in the health field, you can be at even higher risk for having a reaction to this material, which is made from the sap of a latex tree.
Tip: Latex is used for more than medical gloves today. Rubber sink stoppers and other common household items can also contain latex, so be sure to read labels and make educated choices to avoid coming into contact with this material.
Trigger #9: Animal Dander

If you're allergic to cats or dogs, it could be the animal dander or saliva that triggers your symptoms. Despite your reaction, though, you and your pet maybe able to co-exist if your willing to make some extra effort.

Tip: Keep your pet away from your bedroom and also vacuum, clean and dust frequently to remove pet hair and dander that could make you sick

Trigger #10: Medicines

Medicine is supposed to make you feel better, right? But if your body has a problem with an ingredient your medication contains, you can end up dealing with the effects of an allergic reaction, such as hives and even difficulty breathing, instead.  See natural rememdies.

Tip: If you experience hives or any type of rash after taking penicillin or other medications, you should contact your doctor. You may need to try an alternative remedy that uses a different active ingredient to cure whatever ails you.

Yours in health,
Rhonda

How to Battle Allergies

Allergy Season

Do you have a baby or young toddler who is at risk for allergies? Perhaps your little one is predisposed to the condition because of a family history of allergies. If so, you may be going to great lengths to avoid your child's exposure to a host of allergens, including pets. Up until now, researchers have advised this as the best way to help prevent the development of kids' allergies and related symptoms.
But some researchers now are contradicting these earlier recommendations, saying that one of the best things you can do for your newborn may be to raise him or her in the presence of cats or dogs right from an early age. This can actually be an important protective factor in kids' allergies in some cases.
A New Approach

Some of the newest data reveals that when it comes to kids' allergies, children who are exposed to dogs and cats in their first twelve months of life may find that this step helps to protect them from developing allergies and asthma in future years. This is encouraging news, especially since the American College of Allergy, Asthma and Immunology reports that almost three-quarters of all households today have a cat or a dog. But in fact, one pet actually isn't enough to gain the health benefit, according to researchers. Interestingly enough, an article published in the Journal of the American Medical Association (JAMA), found that having only one dog or cat actually increased the risk of having allergies, while having TWO or more pets in the first year significantly decreased the kids' allergies and response to multiple triggers at the age 6 or 7.
Other Prevention Steps

Despite these findings, though, the experts warn that you should talk to your pediatrician first before you run out and invest in a few pets for your baby or toddler.
If you do already have a pet or multiple pets, though, the American Academy of Pediatrics stresses the importance of helping to minimize the allergy risks for young children. For instance, the organization recommends keeping the animals out of your child's bedroom and also cleaning often to remove pet hair and dander.

As an adult .... I am off two prescription allergy meds by just customizing my supplements!  Nutrition can play a big part in how your body responds to allergens. 

Yours in health,
Rhonda

Better Nutrition - Better Moods

Five foods to help depression
There are treatment options that can relieve depression without swallowing pills. Many of the symptoms of depression can be directly linked to vitamin and mineral deficiencies in the standard American diet, which is largely comprised of empty carbs, caffeine and sugar. Depression, mood swings and fatigue often have a common cause: poor nutrition. Avoiding depression or recovering from a depressive episode is often as easy as changing your diet and boosting your consumption of key foods that deliver brain-boosting nutrients and help regulate brain chemistry.

Fish oils: Contain omega-3 fatty acids. Research has shown that depressed people often lack a fatty acid known as EPA. Participants in a 2002 study featured in the Archives of General Psychiatry took just a gram of fish oil each day and noticed a 50-percent decrease in symptoms such as anxiety, sleep disorders, unexplained feelings of sadness, suicidal thoughts, and decreased sex drive. Omega-3 fatty acids can also lower cholesterol and improve cardiovascular health. Get omega-3s through walnuts, flaxseed and oily fish like salmon or tuna.
Brown Rice: Contains vitamins B1 and B3, and folic acid. Brown rice is also a low-glycemic food, which means it releases glucose into the bloodstream gradually, preventing sugar lows and mood swings. Brown rice also provides many of the trace minerals we need to function properly, as well as being a high-fiber food that can keep the digestive system healthy and lower cholesterol. Instant varieties of rice do not offer these benefits. Any time you see "instant" on a food label, avoid it.
Brewer's Yeast: Contains vitamins B1, B2 and B3. Brewer's yeast should be avoided if you do not tolerate yeast well, but if you do, mix a thimbleful into any smoothie for your daily dose. This superfood packs a wide assortment of vitamins and minerals in a small package, including 16 amino acids and 14 minerals. Amino acids are vital for the nervous system, which makes brewer's yeast a no-brainer for treating depression.
Whole-grain oats: Contain folic acid, pantothenic acid and vitamins B6 and B1. Oats help lower cholesterol, are soothing to the digestive tract and help avoid the blood sugar crash-and-burn that can lead to crabbiness and mood swings. Other whole grains such as kamut, spelt and quinoa are also excellent choices for delivering brain-boosting nutrients and avoiding the pitfalls of refined grains such as white flour.
Cabbage: Contains vitamin C and folic acid. Cabbage protects against stress, infection and heart disease, as well as many types of cancers, according to the American Association for Cancer Research. There are numerous ways to get cabbage into your diet; toss it in a salad instead of lettuce, use cabbage in place of lettuce wraps, stir fry it in your favorite Asian dish, make some classic cabbage soup or juice it.
Also worth mentioning: Foods like raw cacao, dark molasses and brazil nuts (high in selenium) are also excellent for boosting brain function and eliminating depression.
Things to avoid:

If you feel you are depressed or at risk for depression, you also need to avoid certain foods and substances. Some commonly prescribed drugs -- such as antibiotics, barbiturates, amphetamines, pain killers, ulcer drugs, anticonvulsants, beta-blockers, anti-Parkinson's drugs, birth control pills, high blood pressure drugs, heart medications and psychotropic drugs -- contribute to depression. If you are taking any of these, don't quit them without talking to your doctor; but be aware that they may be contributing to your condition by depleting your body of depression-fighting vitamins and minerals.
You should also avoid caffeine, smoking and foods high in fat and sugar. Keeping your blood sugar stable and getting B vitamins is important for stabilizing your mood. Cacao can be good for mood because it releases endorphins in the brain, but watch out for milk chocolate and candy varieties high in sugar.

Other non-food things to do:

Get plenty of sunshine. Natural sunlight is a proven cure for depression.
Engage in regular exercise at least three times per week. Exercise lifts and mood and alters brain chemistry in a positive way.
Experience laughter. It's good medicine.

Take a quality superfood supplement to get even more natural medicine from the world of plants.

Are You Wasting Your Money on Vitamins and Minerals?

 

You do NOT need to take vitamins if you are:

 

• In perfect health
• Rarely or never experience stress
• Breathe pure, clean air on a daily basis 
• Eat only organically grown fruits and vegetables that have not been sprayed with pesticides and grown in nutrient depleted soil
• Never eat foods processed with preservatives, dyes, or additives 
• Drink only clean, pure spring water, rather than tap water that has been treated with chlorine, fluoride and other chemicals 
• Refrain from all drugs and poisons including alcohol, tobacco, and caffeine 
• Never take prescribed or over the counter medication with all its damaging side effects

 

Certainly, if this describes you, you are well on your way to living to a ripe old age, disease free. On the other hand, if this does not describe your lifestyle, or even come close, you may benefit from a good quality vitamin/mineral supplement to help compensate for what’s missing in your diet, and to help to detoxify the body from toxins we are exposed to on a daily basis.

 

Each of us has different fingerprints, voices and outward appearances, and internally, we’re just as different. Research suggests that some people may need up to 40 times the amount of certain nutrients than others do, depending on their lifestyles and health concerns.

 

 

 

“Take care of your body, it’s the only place you have to live”

 

~Jim Rohn—Businessman, Author, Speaker, Philosopher ~

For more info write to DNAenhanced@gmail.com

 

 

 

 

The Wrinkle Genes (By Tom Wood, Genewize Affiliate)

Have you ever tried a product that promised you better skin but discovered the results were superficial or non-existent?

You may have even seen a friend get amazing results with a product but when you tried the product nothing happened.

We all react differently to different skin care products because we’re all different. Our DNA proves it.

Specifically there are key genes that make your skin health and aging different from others’. Variations in the “Wrinkle Genes” can tell us which specific nutrients your skin needs to battle your aging process. Based on the results of your genetic skin assessment GeneWize can custom formulate a skin repair serum made exclusively (m.e.) for you. Your skin deserves personal treatment.

Here are the five Wrinkle Genes and how GeneWize customizes nutrients for your formula:

1.Collagen Gene

2.Detox Gene

3.Tissue Gene

4.Inflammation Gene

5.CoQ10 Gene

6.Superoxide Gene

Here are details on each one including which nutrients support the full expression of the gene.
Collagen Gene — MMP1 — the gene helps regulate cell growth, collagen breakdown and photo aging.

Detox Gene — EPHX — Helps determine your skin’s ability to detoxify and protect skin cells against damage from environmental pollutants.

Tissue Gene – GPX1 — this gene protects lung, breast, skin and other tissues by removing and eliminating hydrogen peroxide free radicals.

Inflammation Gene — TNF-A — Time Magazine called inflammation “the secret killer” and it’s definitely not good for skin health. Inflammation over the long term can negatively affect important organs, including the skin.

CoQ10 Gene — NQ01 — Determines which form of CoQ10 (Ubiquinol or Unbiquinone) your body needs. The only way to know this is to run a genetic analysis. If you purchase CoQ10 without knowing the results of this test you are just guessing if it will work for your body.

Superoxide Gene — SOD2 — this gene helps your skin and body defend against oxidative stress by detoxifying super-oxide free radicals (really bad free radicals).

You’ll never find the GeneWize products on the shelf of a store because there are more than 700 possible combinations. Your specific formula is made fresh for you each month based on your DNA assessment.

The only way we market these products is through word-of-mouth because the results are undeniable and people want to tell others about them.

Your formula is 100% active ingredients and contains a liposomal delivery system — the same system used in the patch.

Your custom formulation is $129/mo. If you commit to three months of product there is no charge for the DNA test — $225.

If you are already taking the 12 Gene Healthy Aging m.e. nutritional supplements then adding the m.e. skin serum is just $99/mo and you don’t need to do another DNA test.

Your DNA never changes so you only have to take the test once and your formulation will never change.

Yours in health,
Rhonda

Nicknames for Gene SNPs

Article written by Tom Wood, 4 star business affiliate with Genewize...


I’ve been involved in GeneWize since the beginning and I still can’t tell you the names of all the SNPs we test.

Since I’m a top earner with the company it’s obviously not critical to know what each SNP is, but I’ve become more curious and interested in the science the more I’ve been here.
To help myself out, I’ve nicknamed each SNP so we can remember them. Use this guide to share with your guests and to help you realize and remember all this science does for us.

Bone Strength Gene™ – SNP 1: VDR (Vitamin D Receptor)
Detox Gene™ — SNP 2: EPHX (Microsomal Epoxide Hydrolase)
CoQ10 Gene™ — SNP 3: NQ01 (Coenzyme Q10 Reductase)
Superoxide Gene™ Free Radical Defense — SNP 4: SOD2 (Manganese Superoxide Dimutase)
Lung and Breast Tissue Gene™ — SNP 5: GPX1 (Glutathione Peroxidase 1)
Collagen Health Gene™ — SNP 6: MMP-1 (Matrix Metalloproteinase)
Cardiovascular Gene™ — SNP 7: MTRR ( Methionine Sythase Reductase)
Cardiovascular Enzyme Gene™ — SNP 8: MTHFR (Methylene Tetrahydrofolate Reductase)
Inflammation Response Gene™ — – SNP 9: TNF-a (Tumor Necrosis Factor – a)
Cholesterol Oxidation Gene™ — SNP10: PON-1 (Paraxonase 1)
Blood Pressure Gene™ — – SNP 12: ApoB (Apolipoprotein B)

Bone Strength Gene™ — SNP 1: VDR (Vitamin D Receptor) — The strength of our bones is influenced by the VDR gene. In fact, among healthy people, this one gene accounts for 75% of the entire genetic influence on bone density.i People with SNPs in the VDR gene tend to have lower bone mineral density than those without these variations.ii,iii,iv SNPs in this gene may also influence young adult growth,v parathyroid hormone production,vi normal cell division,vii and blood sugar regulation.
Supportive ingredients include: Calcium (as Calcium Carbonate), Vitamin K1 (as phytonadione), Vitamin D3 (as cholecalciferol).


Detox Gene™ — SNP 2: EPHX (Microsomal Epoxide Hydrolase) — Epoxides are toxic, highly reactive foreign chemicals present in cigarette smoke, car exhaust, charcoal-grilled meat, and smoke from burning wood, pesticides, and alcohol.  The body’s way of dealing with epoxides is through the enzyme microsomal EPHX, which detoxifies these foreign compounds. Due to a SNP on the EPHX gene, people with lowered EPHX activity will have difficulty detoxifying harmful substances and thus be particularly vulnerable to their effects.

Supportive ingredients include: Milk Thistle extract [(Silybum marianum) standardize to 80% silymarin] Oxyphyte® Green Tea extract [(Camellia sinensis) standardized to 90% polyphenols], Broccoli extract [(Brassica oleracea) standardized to 1.2% sulphoraphane], Burdock Root powder (Arctium pubens), Kale powder (Brassica oleracea), Artichoke extract [(Cynara scolymus) standardized to 4% chlorogenic acid/9% caffeoylquinic acid], Schizandra Berry powder (Schisandra chinensis ), Gotu Kola extract (Centella asiatica).

CoQ10 Gene™ — SNP 3: NQ01 (Coenzyme Q10 Reductase) — Free radicals are considered by many scientists to be the primary cause of aging. The coenzyme Q10 reductase (NQO1) enzyme converts coenzyme Q10 (ubiquinone) to its reduced form, ubiquinol, which scavenges free radicals in the mitochondria and lipid membranes.ix Some individuals have a SNP in the NQO1 gene that slows the reduction of ubiquinone to ubiquinol, resulting in very low blood levels of this key antioxidant. Consequently, people with this SNP are at high risk of free radical attack.x Because NQO1 is also involved in the detoxification of compounds foreign to the body, a SNP in the NQO1 gene may cause aberrant cellular changes.

Supportive ingredients: Ubiquinone or Ubiquinol — Depends on which form of CoQ10 your body can metabolize. You don’t know unless you run a genetic test.

Superoxide Gene™ Free Radical Defense – SNP 4: SOD2 (Manganese Superoxide Dimutase) — The SOD2 enzyme is also involved in scavenging free radicals. However, SOD2 is focused on one particularly toxic type of free radical: superoxide.xi Since the superoxide radical is produced in abundance in all cells, it is the starting point for the free radical chain of production. SOD2 has the distinction of being the only enzyme in the mitochondria that can neutralize superoxide.xii Individuals with a SNP in this gene therefore have a weak first line of defense against free radicals.

Supportive ingredients include: Spirulina powder (Arthrospira platensis ), Oxyphyte® Green Tea extract [(Camellia sinensis) standardized to 90% Polyphenols], Oxyphyte® White Tea extract (Camellia sinensis ) standardized to 90% Polyphenols], Bilberry extract [(Vaccinium myrtillus) standardized to 5% anthocyanins], Vitamin B3 (as Niacinamide).

Lung and Breast Tissue Gene™ — SNP 5: GPX1 (Glutathione Peroxidase 1) — The GPX1 antioxidant enzyme specifically scavenges hydrogen peroxide, a reactive oxygen species. GPX1 is a selenoprotein, meaning it incorporates selenium into its protein structure.xiii Therefore, how much GPX1 a person produces is dependent on their selenium level.13 A SNP on the GPX1 gene can reduce a person’s ability to utilize selenium.xiv,xv That means higher-than-normal selenium intake is needed to afford protection to hydrogen peroxide-sensitive tissues, particularly lung and breast tissues.

Supportive ingredients include: Proprietary blend: Citrus Bioflavonoids powder (Citrus limonium, Citrus paradise and Citrus sinensis ), Milk Thistle extract [(Silybum marianum) standardized to 80% silymarin], Astragalus Root powder ( Astragalus membranaceus), Ginkgo Biloba extract [(Ginkgo biloba) standardized to 24% Flavoglycosides/6% Terpene Lactones], Oxyphyte® Grape Skin extract [(Vitis vinifera) standardized to 10% resveratrol], Alpha Lipoic Acid, Organic Blueberry extract [(Vaccinium angustifolium) standardized to 2% polyphenols], Organic Black Currant extract [( Ribes nigrum) standardized to 2% polyphenols], Tumeric extract [(Curcuma longa) standardized to 95% curcumin], Garlic Powder (Allium sativum), Selenium (as Selenium Amino Acid Chelate). Citrus Bioflavonoids powder (Citrus limonium, Citrus paradise and Citrussinensis ), Milk Thistle extract [(Silybum marianum) standardized to 80% silymarin], Astragalus Rootpowder ( Astragalus membranaceus), Ginkgo Biloba extract [(Ginkgo biloba) standardized to24% Flavoglycosides/6% Terpene Lactones], Oxyphyte® Grape Skin extract [(Vitis vinifera) standardizedto 10% resveratrol], Alpha Lipoic Acid, Organic Blueberry extract [(Vaccinium angustifolium) standardized to 2% polyphenols], Organic Black Currant extract [( Ribes nigrum) standardized to 2% polyphenols],Tumeric extract [(Curcuma longa) standardized to 95% curcumin], Garlic Powder (Allium sativum),Selenium (as Selenium Amino Acid Chelate).

Collagen Health Gene™ — SNP 6: MMP-1 (Matrix Metalloproteinase) — Collagen is the main component of cartilage, ligaments, tendons, and bone. It is constantly synthesized and broken down in an on-going cycle. MMP1, also known as collagenase, is an enzyme that degrades collagen. People with a SNP in the MMP1 gene produce collagenase at an increased rate, which means their bodies may break down collagen faster than they can rebuild it.xviii,xix These individuals will likely benefit from added support for collagen-rich structures such as the bones and joints.

Supportive ingredients include: Tomato powder [(Solanum lycopersicum) standardized to 0.8% lycopene], Oxyphyte® White Tea extract [(Camellia sinensis) standardized to 90% polyphenols], Oxyphyte® Grape Seed extract [(Vitis vinifera) standardized to 95% polyphenols].

Cardiovascular Gene ™ — SNP 7: MTRR ( Methionine Sythase Reductase) — Homocysteine is a metabolite of the amino acid methionine. Research has shown it is important to control homocysteine levels in order to preserve cardiovascular health.xx,xxi,xxii One of the body’s methods for keeping homocysteine levels in check is the MTRR enzyme, which transforms homocysteine back to either methionine or cysteine.xxiii When an individual has a SNP in the MTRR gene, their ability to clear homocysteine from the blood may be hindered. However, only certain population groups appear to be negatively affected by this SNP.

Supportive ingredients include: Trimethylglycine, Zinc (as Zinc Amino Acid Chelate), Dong Quai extract [(Angelica sinensis) standardized to 1.0% Ligustilide], Vitamin B3 (as Niacinamide), Vitamin B2, (as Riboflavin), Vitamin B12 (as Cyanocobalamin), Vitamin B6 (as Pyridoxine hydrochloride), Folate (as folic acid). Trimethylglycine, Zinc(as Zinc Amino Acid Chelate), Dong Quai extract [(Angelica sinensis) standardized to 1.0% Ligustilide], Vitamin B3 (as Niacinamide), Vitamin B2, (as Riboflavin), Vitamin B12 (as Cyanocobalamin), Vitamin B6(as Pyridoxine hydrochloride), Folate (as folic acid).

Cardiovascular Enzyme Gene™ — SNP 8: MTHFR (Methylene Tetrahydrofolate Reductase) — Like the MTRR enzyme, the MTHFR enzyme is responsible for reducing blood levels of homocysteine. People with a SNP in the MTHFR gene manufacture defective enzymes that can’t clear homocysteine from the blood efficiently. Research has shown there is a direct association between a SNP in the MRHFR gene and elevated levels of homocysteine,xxvi particularly in those with low levels of folate.

Supportive ingredients include: Trimethylglycine, Choline Bitartrate, L-methlyfolate.

Inflammation Response Gene™ — SNP 9: TNF-a (Tumor Necrosis Factor – a) — Inflammation is a response of the immune system to a perceived attack. While it is a helpful response in the short-term, if inflammation continues on-going, it can negatively affect the cells, tissues, and ultimately, the organs. TNF- is a cytokine (a chemical messenger of the immune system) that plays a role in inflammatory processes. Individuals with a SNP on the TNF- gene may have an over-reactive inflammation mechanism,which can negatively affect the joints,xxviii brain,xxix lungs,xxx and heart.xxxi

Supportive ingredients include: Milk Thistle extract [(Silybum marianum) standardized to 80% Silymarin], Oxyphyte® Green Tea extract [(Camellia sinensis) standardized to 90% Polyphenols], Pomegranate extract [( Punica granatum) standardized to 40% Ellagic Acid], Oxyphyte® Grape Seed extract [(Vitis vinifera) standardized to 95% polyphenols].

Cholesterol Oxidation Gene™ — SNP10: PON-1 (Paraxonase 1) — While it used to be thought that high cholesterol posed a health issue in and of itself, it is now believed that cholesterol only becomes a problem once the cholesterol carrier, low-density lipoprotein (LDL), becomes oxidized (attacked by free radicals). The PON1 enzyme attaches itself to high-density lipoprotein (HDL), which protects both HDL and LDL from oxidation.xxxii Due to common SNPs in the PON1 gene, blood levels of PON1 can vary by a factor of 10 to 40-fold among different individuals.xxxiii,xxxiv Those with low levels of PON1 have higher levels of oxidized LDL, which can lead to diminished cardiovascular health.xxxv,xxxvi

Supportive ingredients include: Organic Reshi Mushroom extract (Granoderma lucidum), Organic Shitake Mushroom extract (Lentinus edodes), Maitake Mushroom extract [(Grifola frondosa) standardized to 20% polysaccharides], Vitamin E (as dl-alpha tocopherol acetate).

Blood Pressure Gene™ — SNP 11: CYP11B2 (Aldosterone Synthase) — Maintaining blood pressure within the normal range is essential to a healthy heart. The CYP11B2 gene encodes an enzyme called aldosterone synthase, which plays a role in regulating blood pressure. A SNP on the CYP11B2 gene can decrease the ability of blood vessels to relax and constrict in response to changing demands for blood flow.xxxvii (For example, extra blood flow is needed during exercise.) That inability of the vessels to respond properly can set the stage for cardiovascular issues down the road.xxxviii

Supportive ingredients include: Potassium (as Tripotassium citrate monohydrate), Organic Hawthorn Berry extract [(Crataegus laevigata) standardized to 1.5% polyphenols/0.5% flavonoids], Magnesium (as Magnesium Citrate), Acerola Cherry Extract [( Malpighia glabra) standardized to 17% Vitamin C], Garlic powder (Allium sativum). Potassium (as Tripotassium citrate monohydrate), Organic Hawthorn Berry extract [(Crataegus laevigata) standardized to 1.5% polyphenols/0.5% flavonoids], Magnesium (as Magnesium Citrate), Acerola Cherry Extract[( Malpighia glabra) standardized to 17% Vitamin C], Garlic powder (Allium sativum).

Cholesterol Gene™ — SNP 12: ApoB (Apolipoprotein B) — Cholesterol is carried through the bloodstream on various lipoproteins: low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very low-density lipoprotein (VLDL). Apolipoproteins make up the protein part of lipoproteins. One of the more researched apolipoproteins is apolipoprotein B (ApoB); it constitutes the protein component of LDL, the “bad” kind of cholesterol carrier. In fact, without ApoB, LDL cannot form. Because people with SNPs on the ApoB gene have higher ApoB levels, they experience moderate increases in total cholesterol, LDL cholesterol, and triglycerides,xxxix,xl,xli,xlii as well as impaired glucose tolerancexliii and increased blood lipid response after meals.xli.

Supportive ingredients include: Oxyphyte® Green Tea extract [(Camellia sinensis) standardized to 90% polyphenols], Pomegranate extract [( Punica granatum) standardized to 40% ellagic acid], Artichoke extract [(Cynara scolymus) standardized to 4% chlorogenic acid/9% caffeolyquinic acid], Oxyphyte® Grape Skin extract [(Vitis vinifera) standardized to 10% resveratrol].

Yours in health,
Rhonda